Colletodiol (Synonyms: (+)-Colletodiol) |
| Catalog No.GC47119 |
A fungal metabolite with immunosuppressive and antiviral activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 21142-67-6
Sample solution is provided at 25 µL, 10mM.
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Colletodiol is a fungal metabolite that has been found in D. grovesii and has immunosuppressant and antiviral activities.1,2 It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s = 12 and 5 µg/ml, respectively).1 Colletodiol inhibits influenza A viral replication in HeLa-IAV-Luc cells.2
1.Fujimoto, H., Nagano, J., Yamaguchi, K., et al.Immunosuppressive components from an ascomycete, Diplogelasinospora grovesiChem. Pharm. Bull.46(3)423-429(1998) 2.Lai, W., Wang, S., and Ye, X.Colletodiol inhibits the replication of influenza A virus WSN/H1N1 by reducing the activity of viral RNA polymeraseWei Sheng Wu Xue Bao53(12)1334-1339(2013)
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
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