Compound 115-7c (Synonyms: 4-(5-((Benzyloxycarbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoic acid) |
| Catalog No.GB40151 |
Compound 115-7c (908074-72-6) acts as an artificial co-chaperone for HSP70. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity. Compound 115-7c is an important probe for understanding HSP70 functions.
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Cas No.: 908074-72-6
Sample solution is provided at 25 µL, 10mM.
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Compound 115-7c (908074-72-6) acts as an artificial co-chaperone for HSP70. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity. Compound 115-7c is an important probe for understanding HSP70 functions.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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