COP1-ATGL modulator 1 |
| Catalog No.GC71427 |
COP1-ATGL modulator 1 (86) est un modulateur oral actif pour l’axe COP1-ATGL.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2946701-09-1
Sample solution is provided at 25 µL, 10mM.
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COP1-ATGL modulator 1 (86) is an orally active modulator for COP1-ATGL axis. COP1-ATGL modulator 1 (86) could increase ATGL protein expression, reduce ATGL ubiquitination and COP1 autoubiquitination, and diminish lipid accumulation in hepatocytes in the nanomolar range.
References:
[1]. Dipayan Sarkar, et al. Discovery and Development of Quinazolinones and Quinazolinediones for Ameliorating Nonalcoholic Fatty Liver Disease (NAFLD) by Modulating COP1-ATGL Axis. J Med Chem. 2023 Dec 28;66(24):16728-16761.
Review for COP1-ATGL modulator 1
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for COP1-ATGL modulator 1
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