COQ7-IN-2 |
| Catalog No.GC62905 |
COQ7-IN-2 (composé 12) est un inhibiteur de COQ7, avec des valeurs IC50 de 7,3 μM et 15,4 μM pour l'accumulation de DMQ10 et UQ10, respectivement .
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Cas No.: 2579696-76-5
Sample solution is provided at 25 µL, 10mM.
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COQ7-IN-2 (compound 12) is an inhibitor of COQ7, witn IC50 values of 7.3 μM and 15.4 μM for DMQ10 and UQ10 accumulation, respectively[1].
COQ7-IN-2 (compound 12) has less growth inhibition against human normal culture cells[1].The substantial DMQ10 accumulation occurred in both PANC-1 cells (8.7% by COQ7-IN-2 (compound 12)) and PC3 cells (14.0% by COQ7-IN-2 (compound 12))[1].
[1]. Keiko Tsuganezawa, et al. Identification of small molecule inhibitors of human COQ7. Bioorg Med Chem. 2020 Jan 1;28(1):115182.
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