CX-5011 (sodium salt) |
Catalog No.GC43334 |
CX-5011 is a highly selective and potent inhibitor of protein kinase CK2 (IC50 = 0.175 nM for native CK2), a pro-survival and anti-apoptotic kinase highly expressed in cancer cells.
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Cas No.: 1333382-30-1
Sample solution is provided at 25 µL, 10mM.
CX-5011 is a highly selective and potent inhibitor of protein kinase CK2 (IC50 = 0.175 nM for native CK2), a pro-survival and anti-apoptotic kinase highly expressed in cancer cells. It was highly selective for CK2 over a panel of 235 protein kinases. It induces apoptosis, has anticancer properties in vitro, and appears to overcome the drug resistance phenotype that is partially induced by CK2.
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