CXL146 |
| Catalog No.GB40165 |
CXL146 is a selective inhibitor of HL60/MX2 cell proliferation by targeting GRP78 overexpression. CXL146 treatment activated the unfolded protein response (UPR). CXL146-induced UPR activation led to a series of downstream events, including extracellular signal-regulated kinase 1/2 and c-Jun N-terminal kinase activation, which contributed to CXL146-induced apoptosis.
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Cas No.: 2244586-41-0
Sample solution is provided at 25 µL, 10mM.
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CXL146 is a selective inhibitor of HL60/MX2 cell proliferation by targeting GRP78 overexpression. CXL146 treatment activated the unfolded protein response (UPR). CXL146-induced UPR activation led to a series of downstream events, including extracellular signal-regulated kinase 1/2 and c-Jun N-terminal kinase activation, which contributed to CXL146-induced apoptosis.
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