Dimethomorph |
Catalog No.GC47231 |
Le diméthomorphe est un fongicide morpholine qui inhibe la formation de parois cellulaires fongiques.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 110488-70-5
Sample solution is provided at 25 µL, 10mM.
Dimethomorph is a morpholine fungicide that inhibits fungal cell wall formation.1 It inhibits mycelial growth of the oomycete fungi P. citrophthora, P. parasitica, P. capsici, and P. infestans (EC50s = 0.14, 0.38, <0.1, and 0.16-0.3 µg/ml, respectively) but is less active against the green algae species C. vulgaris or S. obliquus in vitro (EC50s = 47.46 and 44.87 µg/ml, respectively).2,3,4 It inhibits androgen receptor (AR) activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen (IC20s = 0.263 and 38.5 µM, respectively).5 It is not toxic to rats (LD50 = 3,900 mg/kg) or goldfish (C. auratus; LC50 = >32 µg/ml).4,1
1.Authority, E.F.S.Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethoateEFSA J.4(7)(2006) 2.Matheron, M.E., and Porchas, M.Impact of azoxystrobin, dimethomorph, fluazinam, fosetyl-al, and metalaxyl on growth, sporulation, and zoospore cyst germination of Three phytophthora sppPlant Dis.84(4)454-458(2000) 3.Rekanovi?, E., Poto?nik, I., Milijaševi?-Mar?i?, S., et al.Toxicity of metalaxyl, azoxystrobin, dimethomorph, cymoxanil, zoxamide and mancozeb to Phytophthora infestans isolates from SerbiaJ. Environ. Sci. Health B.47(5)403-409(2012) 4.Yu, X.-B., Hao, K., Ling, F., et al.Aquatic environmental safety assessment and inhibition mechanism of chemicals for targeting Microcystis aeruginosaEcotoxicology23(9)1638-1647(2014) 5.Orton, F., Rosivatz, E., Scholze, M., et al.Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogensEnviron. Health Perspect.119(6)794-800(2011)
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