DP-C-4 |
| Catalog No.GC62942 |
DP-C-4 est un double PROTAC basé sur Cereblon pour la dégradation simultanée de l'EGFR et du PARP.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1].
DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1].
[1]. Mengzhu Zheng, et al. Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP. J Med Chem. 2021 May 26.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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