ELA-32(human) TFA |
| Catalog No.GC65922 |
L'ELA-32 (humain) TFA est un puissant agoniste du récepteur de l'apéline de haute affinité (IC50 = 0,27 nM ; Kd = 0,51 nM). ELA-32 (humain) TFA ne présente aucune liaison GPR15 et GPR25. ELA-32 (humain) TFA active la voie PI3K/AKT et favorise l'auto-renouvellement des CSEh via la progression du cycle cellulaire et la traduction des protéines. ELA-32 (humain) TFA potentialise également le TGFβ ; voie, amorÇant les CSEh vers la lignée de l'endoderme. ELA-32 (humain) TFA stimule l'angiogenèse dans les cellules HUVEC.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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ELA-32(human) TFA is a potent, high affinity apelin receptor agonist (IC50=0.27 nM; Kd=0.51 nM). ELA-32(human) TFA exhibits no binding GPR15 and GPR25. ELA-32(human) TFA activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein translation. ELA-32(human) TFA also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. ELA-32(human) TFA stimulates angiogenesis in HUVEC cells.
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