ER176 |
| Catalog No.GC70843 |
ER176 est un radioligand PET de nouvelle génération pour l’imagerie de la protéine translocalisatrice 18 kDa (TSPO), un biomarqueur pour la neuroinflammation.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1373887-29-6
Sample solution is provided at 25 µL, 10mM.
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ER176 shows homozygous high-affinity binders (HABs)/heterozygous mixed affinity binders (MABs) ratio for BP ND (specific-to-non-displaceable ratio of distribution volumes) of 1.2[1].
References:
[1]. Masahiro Fujita, et al. Comparison of four 11 C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios. EJNMM
[2]. Jason C Mixdorf, et al. Alternative strategies for the synthesis of [ 11 C]ER176 for PET imaging of neuroinflammation. Appl Radiat Isot. 2021 Sep 17;178:109954.
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