ERRγ agonist-1 |
Catalog No.GC70943 |
ERRγ agonist-1 est un puissant agoniste ERRγ.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
ERRγ agonist-1 (compound 5d) (5 µM; 3 days) significantly increases the expression of tyrosine hydroxylase (TH) and dopamine transporter (DAT), DAergic neuronal phenotypes (dopaminergic neuronal phenotype) in neuroblastoma SH-SY5Y cells[1].
ERRγ agonist-1 (5 µM; 3 days) induces DAergic neuronal phenotypes via the ERRγ-mediated up-regulation of CREB-signaling pathway[1].
References:
[1]. Kim T, et al. Discovery of new ERRγ agonists regulating dopaminergic neuronal phenotype in SH-SY5Y cells. Bioorg Chem. 2022; 122:105716.
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