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ERRγ agonist-1

Catalog No.GC70943

ERRγ agonist-1 est un puissant agoniste ERRγ.

Products are for research use only. Not for human use. We do not sell to patients.

ERRγ agonist-1 Chemical Structure

Taille Prix Stock Qté
10mM (in 1mL DMSO)
246,00 $US
En stock
5 mg
223,00 $US
En stock
10 mg
358,00 $US
En stock
25 mg
716,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
ERRγ agonist-1 is a potent ERRγ agonist. ERRγ agonist-1 increases transcriptional activities of ERRγ. ERRγ agonist-1 has the potential for the research of neuropsychological disorders.

ERRγ agonist-1 (compound 5d) (5 µM; 3 days) significantly increases the expression of tyrosine hydroxylase (TH) and dopamine transporter (DAT), DAergic neuronal phenotypes (dopaminergic neuronal phenotype) in neuroblastoma SH-SY5Y cells[1].
ERRγ agonist-1 (5 µM; 3 days) induces DAergic neuronal phenotypes via the ERRγ-mediated up-regulation of CREB-signaling pathway[1].

References:
[1]. Kim T, et al. Discovery of new ERRγ agonists regulating dopaminergic neuronal phenotype in SH-SY5Y cells. Bioorg Chem. 2022; 122:105716.

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