Erythromycin (Synonyms: NSC 55929) |
| Catalog No.GC12946 |
L'érythromycine est un antibiotique macrolide produit par l'actinomycète Streptomyces erythreus avec un large spectre d'activité antimicrobienne.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 114-07-8
Sample solution is provided at 25 µL, 10mM.
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Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1].
Erythromycin inhibits growth of P. falciparum with IC50 and IC90 values of 58.2 μM and 104.0 μM, respectively[1].
References:
[1]. Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89.
[2]. Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28.
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