Fengabine |
| Catalog No.GC70546 |
Fengabine est un antidépresseur gabaérgique.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 80018-06-0
Sample solution is provided at 25 µL, 10mM.
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Fengabine (50 mg/kg; i.p.; 2 days) prevents completely the learned helplessness induced by the unavoidable shock[1].
Fengabine (150 mg/kg; i.p) decreases the percentage of time spent. Fengabine (25~50 mg/kg; i.p.) reverses the deficit in learning the step-down avoidance task[1].
References:
[1]. Ascalone V, et al. Determination of the GABAergic antidepressant drug fengabine and some of its metabolites in plasma by capillary gas chromatography with electron-capture detection. J Chromatogr. 1989;490(1):81-90.
[2]. Lloyd KG, et al. Fengabine, a novel antidepressant GABAergic agent. I. Activity in models for antidepressant drugs and psychopharmacological profile. J Pharmacol Exp Ther. 1987;241(1):245-250.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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