Fentiazac |
| Catalog No.GC70465 |
Fentiazac Le dérivé de l'acide alcanoïque est un anti - inflammatoire non stéroïdien actif par voie orale qui possède des activités analgésiques, antipyrétiques et antiplaquettaires.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 18046-21-4
Sample solution is provided at 25 µL, 10mM.
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Fentiazac is well tolerated after repeated oral administration in rats, monkeys and dogs; and no significant modifications in the heart and bone marrow function, as well as blood chemistry[1].
Tolerance of Fentiazac in rat, monkey and dog[1].
| Species | Tolerant dosage | Tolerant administration day |
| Rat | 0-50 mg/kg/day | 90 days |
| Red pated monkey | 40 mg/kg/day | 90 days |
| 0-30 mg/kg/day | 180 days | |
| African green monkey | 0-8 mg/kg/day | 79 to 93 days |
| dog | 16.6 mg/kg/day | 180 days |
References:
[1]. Emilio Marmo, et al. Experimental and clinical pharmacology of fentiazac, a new, non-steroidal anti-inflammatory agent. Current Medical Research and Opinion.Volume 6, 1979 - Issue sup2.
[2]. Gabor Katona, et al. Efficacy and tolerability of fentiazac in rheumatoid arthritis: Double-blind study versus indomethacin. Current Medical Research and Opinion. Volume 6, 1979 - Issue sup2.
[3]. Famaey JP, Gaci O, Ginsberg F. Fentiazac in the treatment of osteoarthritis and tendinitis. Curr Med Res Opin. 1983;8(9):675-81.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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