FINDY |
| Catalog No.GC71197 |
FINDY est un inhibiteur sélectif intermédiaire pliant de DYRK1A.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1507367-37-4
Sample solution is provided at 25 µL, 10mM.
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FINDY is a folding intermediate-selective inhibitor of DYRK1A. FINDY can inhibit Ser97 autophosphorylation with an IC50 value of 35 μM. FINDY can be used for the research of neurological disorder. FINDY is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
FINDY (Compound 1) inhibits Ser97 autophosphorylation with an IC50 value of 35 μM[1].
References:
[1]. Yuka Miyazaki, et al. Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. Eur J Med Chem. 2022 Jan 5;227:113948.
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