Fosfomycin Trometamol (Synonyms: Fosfomycin Tromethamine) |
Catalog No.GC43698 |
La fosfomycine (MK-0955) trométhamine est un antibiotique À large spectre qui pénètre dans la barrière hémato-encéphalique en inhibant de manière irréversible un stade précoce de la synthèse de la paroi cellulaire.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 78964-85-9
Sample solution is provided at 25 µL, 10mM.
Fosfomycin trometamol is a broad-spectrum antibiotic that is active against Gram-negative and Gram-positive bacteria with MIC90 values of 8, 32, 4, and 32 µg/mL for ESBL E. coli, carbapenemase-producing K. pneumoniae, P. mirabilis, and methicillin-resistant S. saprophyticus, respectively, in a broth microdilution assay. It is an inhibitor of uridine diphospho-N-acetyl-D-glucosamine enolpyruvyl transferase (MurA) that enters cells via the glycerol-3-phosphate and hexose-6-phosphate transporters. Formulations containing fosfomycin trometamol have been used in the treatment of urinary tract infections.
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