C-11 |
| Catalog No.GC35574 |
C-11 est un inhibiteur de la tubuline et agit comme une cytotoxine ADC, affiche une cytotoxicité pour les lignées cellulaires de carcinome.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2007965-97-9
Sample solution is provided at 25 µL, 10mM.
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C-11 is a tubulysin-based drug-linker conjugate for ADC, displays cytotoxicity for carcinoma cell lines[1].
C-11 exhibits cytotoxicity for N87 cells and MDA-MB-361-DYT2 cells with IC50s of 1.11 nM and 0.9 nM, respectively[1].
[1]. Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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