E3 ligase Ligand 8 |
| Catalog No.GC35933 |
E3 ligase Ligand 8 est un ligand de l'ubiquitine ligase E3. Le ligand 8 de la ligase E3 peut être connecté au ligand de la protéine par un lieur pour former des PROTAC. Les PROTAC sont des inducteurs de la dégradation médiée par l'ubiquitination des protéines favorisant le cancer.
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Cas No.: 1225383-33-4
Sample solution is provided at 25 µL, 10mM.
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E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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