Isoscopoletin (Synonyms: Esculetin 7-methyl ether, 7-methoxy-6-Hydroxycoumarin, 7-Methoxyesculetin) |
| Catalog No.GC36342 |
L'isoscopolétine (6-hydroxy-7-méthoxycoumarine) est un constituant actif des feuilles d'Artemisia argyi.
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Cas No.: 776-86-3
Sample solution is provided at 25 µL, 10mM.
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Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC50s of 4.0 μM and 1.6 μM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively[1]. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication[2].
[1]. Adams M, et al. Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi. Planta Med. 2006 Jul;72(9):862-4. [2]. Li H, et al. Evaluation of antiviral activity of compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus. Planta Med. 2005 Dec;71(12):1128-33.
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