Loxoprofen |
| Catalog No.GC36482 |
Le loxoprofène est un agent anti-inflammatoire non stéroÏdien, actif par voie orale, doté de propriétés analgésiques et antipyrétiques.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 68767-14-6
Sample solution is provided at 25 µL, 10mM.
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Loxoprofen is a non-steroidal anti-inflammatory drug.Target: COXLoxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. Loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. COX-1|6.5 μM (IC50, in human whole blood)|COX-2|13.5 μM (IC50, in human whole blood)
[1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3.
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