LXRβ agonist-2 |
| Catalog No.GC36499 |
LXRβ agonist-2 est un agoniste très puissant et β-sélectif du récepteur X du foie (LXRβ) avec une CE50 de 7 nM, affiche une sélectivité de 28,5 fois par rapport à LXRα (CE50 \u003d 200 nM) et est utilisé dans le traitement de l'athérosclérose.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1949801-52-8
Sample solution is provided at 25 µL, 10mM.
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LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM, displays 28.5-fold selectivity over LXRα (EC50=200 nM) and used in the treatment of atherosclerosis[1]. EC50: 7 nM (LXRβ), 200 nM (LXRα)[1]
[1]. Koura M,et al. Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency and β-selectivity of liver X receptor agonist. Bioorg Med Chem. 2016 Aug 15;24(16):3436-46.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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