Oleanolic acid derivative 2 |
| Catalog No.GC36796 |
Le dérivé d'acide oléanolique 2 est un dérivé d'acide oléanolique, qui est une nouvelle molécule hybride triterpénoÏde-stéroÏde.
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Cas No.: 211516-63-1
Sample solution is provided at 25 µL, 10mM.
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Oleanolic acid derivative 2 is an oleanolic acid derivative, which is a novel triterpenoid-steroid hybrid molecule.
Oleanolic acid suppress transcription or translation of inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) genes. extracted from the reference, compound 12a. For the transformation of olefin 9a into ketone 12a , the obvious ozonolysis cannot be used because ozone also reacts with the C-12 olefin of oleanane triterpenoids to give the 12R,13R-epoxide, 12-ketone,9 and 12R-hydroxy lactone.[1].
[1]. Tadashi Honda, et al. Design and Synthesis of 23,24-Dinoroleanolic Acid Derivatives, Novel Triterpenoid-Steroid Hybrid Molecules. J. Org. Chem., 1998, 63 (14), pp 4846-4849.
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