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Octacosane

Catalog No.GD19226

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Octacosane Chemical Structure

Cas No.: 630-02-4

Taille Prix Stock Qté
10g
90,00 $US
En stock
50g
309,00 $US
En stock
250g
1 081,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products
Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l.

Octacosane (12.5-100 渭g/ml; 18 h) displays strong cytotoxic activity on B16F10-Nex2 cells, with an IC50 value of 41.08 渭g/ml[1].

Octacosane (500 渭g; injected at peripheral sites in relation to the original cell grafting; daily; 35 days) results in a significant delay of tumor progression with a significant antitumor effect[1].

[1]. Carlos R Figueiredo, et al. Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo. Pharmacogn Mag. 2014 Apr;10(Suppl 2):S363-76.  

[2]. S Rajkumar, et al. Mosquitocidal activities of octacosane from Moschosma polystachyum Linn (lamiaceae). J Ethnopharmacol. 2004 Jan;90(1):87-9. 

[3]. Sameh S M Soliman, et al. Effective targeting of breast cancer cells (MCF7) via novel biogenic synthesis of gold nanoparticles using cancer-derived metabolites. PLoS One. 2020 Oct 6;15(10):e0240156. 

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