Bucolome (Synonyms: 5-Butyl-1-cyclohexylbarbituric acid) |
| Catalog No.GF15653 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 841-73-6
Sample solution is provided at 25 µL, 10mM.
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Bucolome is a CYP2C9 inhibitor, used as an uricosuric agent or anti-inflammatory agent.
Bucolome is a potent mixed-type inhibitor for (S)-warfarin 7-hydroxylation, with Ki of 8.2 and 20.2 渭M, respectively[1].
[1]. Takahashi H, et al. Pharmacokinetic interaction between warfarin and a uricosuric agent, bucolome: application of In vitro approaches to predicting In vivo reduction of (S)-warfarin clearance. Drug Metab Dispos. 1999 Oct;27(10):1179-86.
Review for Bucolome
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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