(S)-2-Amino-4-(3-hydroxyguanidino)butanoic acid dihydrochloride |
| Catalog No.GF48934 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 291758-32-2
Sample solution is provided at 25 µL, 10mM.
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nor-NOHA dihydrochloride is a selective and reversible arginase inhibitor. nor-NOHA dihydrochloride induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride can used in study endothelial dysfunction, immunosuppression and metabolism.
[1]. Ng KP, et al. The arginase inhibitor N蠅-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. PLoS One. 2018 Oct 11;13(10):e0205254.
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