GPR139 agonist-2 |
| Catalog No.GC71095 |
GPR139 agonist-2 (composé 20A) est un puissant agoniste du gpr139 avec une CE50 de 24,7 nm.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2983118-29-0
Sample solution is provided at 25 µL, 10mM.
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GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research.
References:
[1]. Jianhang Mao, et al. Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Interaction and Cognitive Impairment. J Med Chem. 2023 Oct 26;66(20):14011-14028.
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