GSK J2 |
| Catalog No.GC13086 |
GSK J2 est un isomère de GSK-J1 qui n'a pas d'activité spécifique. GSK-J1 est un puissant inhibiteur des H3K27me3/me2-déméthylases JMJD3/KDM6B et UTX/KDM6A.
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Cas No.: 1394854-52-4
Sample solution is provided at 25 µL, 10mM.
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GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
GSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC50 of > 100 μM and 49 μM, respectively[1].
References:
[1]. Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2.
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