Guanosine 5'-diphosphate sodium (Synonyms: GDP sodium) |
Catalog No.GC66869 |
La guanosine 5'-diphosphate (GDP) de sodium est un nucléoside diphosphate qui active le canal K+ sensible à l'adénosine 5'-triphosphate. La guanosine 577777#39;-diphosphate de sodium est un mobilisateur potentiel du fer, qui empêche l'interaction hepcidine-ferroportine et module la voie interleukine-6 \u200b\u200b(IL-6)/stat-3. La guanosine 577777#39;-diphosphate de sodium peut être utilisée dans la recherche de l'inflammation, telle que l'anémie inflammatoire (AI).
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Cas No.: 43139-22-6
Sample solution is provided at 25 µL, 10mM.
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].
[1]. S Kajioka, et al. Guanosine diphosphate activates an adenosine 5'-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418.
[2]. Angmo S, et al. Identification of Guanosine 5'-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.
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