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Iberiotoxin TFA

Catalog No.GC72091

Iberiotoxin TFA est un Inhibiteur sélectif du canal K + activé par Ca2 + à haute conductivité, avec KD de ~ 1 nm.

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Iberiotoxin TFA Chemical Structure

Taille Prix Stock Qté
100 µg
342,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Iberiotoxin (TFA) is a selective high conductance high conductance Ca2+-activated K+ channel inhibitor with a Kd of ~1 nM. Iberiotoxin (TFA) does not block other types of voltage-dependent ion channels.

References:
[1]. Galvez A, et al. Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. J Biol Chem. 1990;265(19):11083-11090.
[2]. Echeverry S, et al. Activation of BK Channel Contributes to PL-Induced Mesenchymal Stem Cell Migration. Front Physiol. 2020;11:210.
[3]. Wang RJ, et al. Downregulation of large conductance calcium-activated potassium channels in paraventricular nucleus contributes to sympathoexcitation in rats with chronic heart failure. Zhonghua Xin Xue Guan Bing Za Zhi. 2018;46(3):178-186.

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