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IMPDH2-IN-2

Catalog No.GC70917

IMPDH2-IN-2 est un inhibiteur puissant de l’inosine 5’-monophosphate déshydrogénase (IMPDH) avec une valeur de Ki,app de 14 μM, respectivement.

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IMPDH2-IN-2 Chemical Structure

Cas No.: 1434517-02-8

Taille Prix Stock Qté
1 mg
108,00 $US
En stock
5 mg
270,00 $US
En stock
10 mg
441,00 $US
En stock
25 mg
882,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
IMPDH2-IN-2 is a potent inhibitor of inosine 5’-monophosphate dehydrogenase (IMPDH) with a Ki,app value of 14 μM, respectively. IMPDH2-IN-2 displays moderate antibacterial activity (MIC = 6.3 and 11 μM in minimal GAST/Fe and rich 7H9/ADC/Tween media, respectively). IMPDH2-IN-2 is a potential anti-tuberculosis agent.

References:
[1]. Chacko S, et al. Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents [published correction appears in J Med Chem. 2021 Dec 23;64(24):18233-18234]. J Med Chem. 2018;61(11):4739-4756.

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