Accueil>>Signaling Pathways>> Chromatin/Epigenetics>> Epigenetic Reader Domain>>Ischemin sodium

Ischemin sodium

Catalog No.GC70314

Ischemin sodium est un inhibiteur de bromodomaine CBP qui inhibe l’interaction p53 avec CBP et l’activité transcriptionnelle dans les cellules.

Products are for research use only. Not for human use. We do not sell to patients.

Ischemin sodium Chemical Structure

Taille Prix Stock Qté
5 mg
231,00 $US
En stock
10 mg
365,00 $US
En stock

Tel:(909) 407-4943 Email: sales@glpbio.com

Avis des clients

Based on customer reviews.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Ischemin sodium is a CBP bromodomain inhibitor that inhibits p53 interaction with CBP and transcriptional activity in cells. Ischemin sodium salt inhibits p53-induced p21 activation with an IC50 value of 5 µM. Ischemin sodium salt also prevents apoptosis in ischemic cardiomyocytes. Ischemin sodium salt can be used in the study of cardiovascular diseases (such as myocardial ischemia).

Ischemin sodium (50, 100 µM; 24 h) inhibits p53 activation on DNA damaging stress in U2OS cells[1].
Ischemin sodium (10 μM; 3 days) blocks apoptosis in cardiomyocytes by inhibiting caspase 3/7 activity[1].
Ischemin sodium salt inhibits p53 cellular signaling pathways in U2OS cells[1].

Avis

Review for Ischemin sodium

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for Ischemin sodium

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.