JNJ-1013 |
Catalog No.GC69316 |
JNJ-1013 est un inhibiteur de dégradation sélectif efficace d'IRAK1, avec des valeurs IC50 respectives de 72, 443 et 1071 nM pour IRAK1, IRAK4 et VHL FP. JNJ-1013 induit l'apoptose cellulaire et augmente l'expression de PARP clivé. JNJ-1013 réduit l'expression d'IRAK1, p-IKBα et pSTAT3(Tyr705).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2597343-08-1
Sample solution is provided at 25 µL, 10mM.
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