M1002 |
Catalog No.GC65046 |
M1002 est un agoniste du facteur 2 induit par l'hypoxie (HIF-2) et peut améliorer l'expression des gènes cibles de HIF-2. M1002 présente une synergie avec les inhibiteurs du domaine prolyl-hydroxylase (PHD).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 823830-85-9
Sample solution is provided at 25 µL, 10mM.
M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors[1].
M1002 (10 μM; 24 h) enhances the expression of HIF-2 target genes with great efficacy[1].M1002 (5 μM; 24 h) treatment shows synergy with prolyl hydroxylase domain (PHD) inhibitors[1].
[1]. Dalei Wu, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Apr;15(4):367-376.
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *