MA220607 |
Catalog No.GC71098 |
MA220607 est un agent antimicrobien avec une faible toxicité hémolytique et un mécanisme d'action double cible (MOA).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2922826-56-8
Sample solution is provided at 25 µL, 10mM.
MA220607 is an antibacterial agent with low hemolytic toxicity and a dual-target mechanism of action (MOA). MA220607 promotes FtsZ protein polymerization, also increases the permeability of bacterial membranes and inhibits biofilm formation. The resistance rate of MA220607 is low, and the MICs against Gram-positive bacteria and Gram-negative bacteria are Table 0.062-2 μg/mL and 0.5-4 μg/mL, respectively).
References:
[1]. Ma Y et al. New broad-spectrum and potent antibacterial agents with dual-targeting mechanism: Promoting FtsZ polymerization and disrupting bacterial membranes. Eur J Med Chem. 2023 Nov 7;263:115930.
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