MitoNeoD (Synonyms: MitoNeoD; Mito-NeoD; Mito Neo D; Mito-Neo-D; Mito Neo-D) |
| Catalog No.GB62268 |
MitoNeoD is a novel mitochondria-targeted O2(⋅-) probe that can be used in vivo.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2375088-89-2
Sample solution is provided at 25 µL, 10mM.
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MitoNeoD is a novel mitochondria-targeted O2(⋅-) probe that can be used in vivo. It prevents DNA intercalation. MitoNeoD incorporates a carbon-deuterium bond, and enhances O2(⋅-) selectivity. MitoNeoD comprises a O2⋅--sensitive reduced phenanthridinium moiety modified to prevent DNA intercalation, as well as a carbon-deuterium bond to enhance its selectivity for O2⋅- over non-specific oxidation, and a triphenylphosphonium lipophilic cation moiety leading to the rapid accumulation within mitochondria. MitoNeoD is a versatile and robust probe to assess changes in mitochondrial O2⋅- from isolated mitochondria to animal models, thus offering a way to examine the many roles of mitochondrial O2⋅- production in health and disease.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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