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mmu-miR-1191a antagomir

Catalog No.GC72477

mmu-miR-1191a antagomir sont des oligonucléotides modifiés chimiquement qui s’hybrident avec des miRNAs matures.

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mmu-miR-1191a antagomir Chemical Structure

Taille Prix Stock Qté
5 nmol
162,00 $US
En stock
20 nmol
405,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
mmu-miR-1191a antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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