Naloxone-d5 (Synonyms: N-Allyldihydro-14-hydroxynormorphinone-d5) |
Catalog No.GC47743 |
An Analytical Reference Material
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1261079-38-2
Sample solution is provided at 25 µL, 10mM.
Naloxone-d5 is an analytical reference material intended for use as an internal standard for the quantification of naloxone by GC- or LC-MS. Naloxone is categorized as an opioid antagonist.1 Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose.2,3 They have also been used in combination with buprenorphine in the treatment of opiate addiction and in pain management.4,5 This product is intended for research and forensic applications.
1.Le Bourdonnec, B., Barker, W.M., Belanger, S., et al.Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as μ opioid receptor antagonists with improved opioid receptor selectivity profilesBioorg. Med. Chem. Lett.18(6)2006-2012(2008) 2.Boyer, E.W.Management of opioid analgesic overdoseN. Engl. J. Med.367(2)146-155(2012) 3.Bowman, S., Eiserman, J., Beletsky, L., et al.Reducing the health consequences of opioid addiction in primary careAm. J. Med.126(7)565-571(2013) 4.Bart, G.Maintenance medication for opiate addiction: The foundation of recoveryJ. Addict. Dis.31(3)207-225(2012) 5.Chen, K.Y., Chen, L., and Mao, J.Buprenorphine-naloxone therapy in pain managementAnesthesiology120(5)1262-1274(2014)
Average Rating: 5
(Based on Reviews and 22 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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