NCL 00017509 |
| Catalog No.GC50112 |
NCL 00017509 (composé 6) est un inhibiteur puissant et irréversible de Nek2 ((Never in mitosis gene a)-related kinase 2).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1507367-00-1
Sample solution is provided at 25 µL, 10mM.
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Potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo.
Lebraud et al (2014) Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles. Org.Biomol.Chem. 12 141 PMID:24213855
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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