Nerolidol (Synonyms: (±)-Nerolidol) |
| Catalog No.GC41343 |
Le nérolidol est un sesquiterpène naturel actif sur la membrane, avec une activité antitumorale, antibactérienne, antifongique et antiparasitaire.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7212-44-4
Sample solution is provided at 25 µL, 10mM.
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Nerolidol is a sesquiterpene found in a variety of plants, including C. sativa, that has diverse biological activities, including antioxidant, anthelmintic, antinociceptive, and anti-inflammatory properties. It decreases superoxide dismutase (SOD) and catalase activity, reduces glutathione (GSH) levels, and increases malondialdehyde (MDA) levels in the brain when administered at a dose of 50 mg/kg in a rat model of Parkinson's disease induced by rotenone . It also inhibits rotenone-induced increases in IL-1β, IL-6, and TNF-α in rat brain. Nerolidol (100, 200, and 400 mg/kg) reduces worm burden and egg production in a mouse model of schistosomiasis. It also decreases acetic acid-induced writhing and formalin-induced licking time in mice, indicating antinociceptive activity, and reduced carrageenan-induced paw edema when administered at doses of 300 and 400 mg/kg. Formulations containing nerolidol have been used as fragrance ingredients.
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