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Odesivimab

Catalog No.GC72434

Odesivimab is a human monoclonal antibody, targeting Ebola virus glycoprotein with a KD value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein.

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Odesivimab Chemical Structure

Cas No.: 2135632-30-1

Taille Prix Stock Qté
1 mg
270,00 $US
En stock
5 mg
702,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Odesivimab is a human monoclonal antibody, targeting Ebola virus glycoprotein with a KD value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein. Odesivimab can be used in research of Ebola virus infection.

Odesivimab (REGN-3471) neutralizes pseudovirus particles in vitro. Odesivimab with Atoltivimab and Maftivimab has an IC50 value of 0.39 nM[1].

Odesivimab with Atoltivimab and Maftivimab (REGN-3471; 50 mg/kg) has protective effect in the rhesus macaque model of Ebola virus infection[1].

References:
[1]. Markham A. REGN-EB3: First Approval. Drugs. 2021 Jan;81(1):175-178.

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