Accueil>>ODN 24888

ODN 24888

Catalog No.GC71137

ODN 24888 est un oligonucléotide inhibiteur modifié par la Guanine (INH - ODN).

Products are for research use only. Not for human use. We do not sell to patients.

ODN 24888 Chemical Structure

Cas No.: 1964506-30-6

Taille Prix Stock Qté
1 mg
281,00 $US
En stock

Tel:(909) 407-4943 Email: sales@glpbio.com

Avis des clients

Based on customer reviews.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
ODN 24888 is an guanine-modified inhibitory oligonucleotides (INH-ODN), shows potent inhibition on TLR7/TLR9-mediated signaling. ODN 24888 impairs IFN-α level and NF-κB activation, inhibits IL-6 release. ODN 24888 involves in immune and inflammatory responses, can be used as a vaccine adjuvant.

References:
[1]. Saul Meike, et al. Reduction of bone resorption, especially in chronic joint diseases: Germany, DE102019122014 A1. 2021-02-18.
[2]. Römmler F, et al. Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated im mune responses of human immune cells. PLoS One. 2015 Feb 19;10(2):e0116703.

Avis

Review for ODN 24888

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for ODN 24888

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.