P-CAB agent 2 |
Catalog No.GC71225 |
P-CAB agent 2 est un puissant bloqueur d'acide compétitif de potassium actif par voie orale et un inhibiteur de la sécrétion d'acide gastrique.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1978371-23-1
Sample solution is provided at 25 µL, 10mM.
P-CAB agent 2 (100 µM) inhibits the hERG potassium channel with an inhibition rate of 86.21% and an IC50 value of 18.69 M[1].
P-CAB agent 2 (example 1) inhibits histamine -induced gastric acid secretion in SD rats[1].
P-CAB agent 2 (600, 2000 mg/kg; p.o.; once) shows no acute toxicity and 600mg/kg shows no significant effect on animal body weight in SD rats[1].
References:
[1]. YinLin Qin, et al. Pyrrole sulfonyl derivative, and preparation method and medical use thereof. WO2016119505A1.
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