p-methyl-N-salicyloyl Tryptamine |
| Catalog No.GC91070 |
Un agent neuroprotecteur
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1371564-45-2
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
p-metl-N-salicyloyl Tryptamine is a neuroprotective agent and derivative of N-salicyloyl tryptamine.1 It reduces LPS-induced nitric oxide (NO) production in C6 rat glioma cells and BV-2 mouse microglia (IC50s = 7.48 and 4.94 µM, respectively). It also reduces LPS-induced production of TNF-α and prostaglandin E2 and increases production of IL-10 in BV-2 microglia when used at a concentration of 40 µM. In vivo, p-metl-N-salicyloyl tryptamine (25-100 mg/kg) decreases cortical and hippocampal amyloid-β (Aβ) plaque formation and neuronal pyroptosis, as well as improves spatial learning and memory, in a mouse model of Aβ-induced Alzheimer’s disease.2
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *