PDD 00017238 |
| Catalog No.GC50638 |
Le PDD 00017238 est un puissant inhibiteur de la poly(ADP-ribose) glycohydrolase (PARG), avec des valeurs EC50 de 40 nM et 55 nM en dosage biochimique et POM cellulaire, respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1952247-05-0
Sample solution is provided at 25 µL, 10mM.
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High affinity and potent PARG inhibitor (Kd = 3.09 nM; IC50 = 40 nM). Negative control PDD 00031705 also available.
James et al (2016) First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib. ACS Chem.Biol. 11 3179 PMID:27689388
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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