Pep 2-8 (Synonyms: TVFTSWEEYLDWV-NH2) |
| Catalog No.GC50447 |
Pep 2-8 est un inhibiteur de PCSK9 avec un KD de liaison de 0,7 μM et une IC50 de 1,4 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1541011-97-5
Sample solution is provided at 25 µL, 10mM.
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Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
Zhang et al (2014) Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J.Biol.Chem. 289 942 PMID:24225950
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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