Pep2-8 TFA |
| Catalog No.GC72140 |
Pep2-8 TFA est un peptide qui a renforcé l’activité antagoniste de proprotéine convertase subtilin/ kexin 9 type (PCSK9).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Pep2-8 TFA binds to C-terminally truncated PCSK9[1].
Pep2-8 TFA restored LDL uptake of PCSK9-treated HepG2 cells to about 90% of control activity at a concentration of 50 μM[1].
References:
[1]. Lammi C, et al. Biological Characterization of Computationally Designed Analogs of peptide TVFTSWEEYLDWV (Pep2-8) with Increased PCSK9 Antagonistic Activity. Sci Rep. 2019 Feb 20;9(1):2343.
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