Pirepemat (Synonyms: IRL752) |
Catalog No.GC63323 |
Le pirepemat (IRL752) est un agent favorisant les catécholamines et la cognition qui favorise le cortex.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1227638-29-0
Sample solution is provided at 25 µL, 10mM.
Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson’s disease[1][2].
IRL752 displayed its highest in vitro affinities for 5-HT and NA-related targets[2].
IRL752 (3.7-100 µmol/kg, s.c.) has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reversed deficits resulting from hypomonoaminergic function[2].
[1]. Ipsen and IRLAB Enter Exclusive Worldwide Licensing Agreement Aimed to Improve the Lives of People Living with Parkinson’s Disease.
[2]. S Hjorth, et al. (3 S)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine (IRL752) -a Novel Cortical-Preferring Catecholamine Transmission- and Cognition-Promoting Agent. J Pharmacol Exp Ther. 2020 Sep;374(3):404-419.
Average Rating: 5
(Based on Reviews and 7 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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