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Pirepemat (Synonyms: IRL752)

Catalog No.GC63323

Le pirepemat (IRL752) est un agent favorisant les catécholamines et la cognition qui favorise le cortex.

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Pirepemat Chemical Structure

Cas No.: 1227638-29-0

Taille Prix Stock Qté
5 mg
270,00 $US
En stock
10 mg
432,00 $US
En stock
25 mg
855,00 $US
En stock
50 mg
1 305,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson’s disease[1][2].

IRL752 displayed its highest in vitro affinities for 5-HT and NA-related targets[2].

IRL752 (3.7-100 µmol/kg, s.c.) has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reversed deficits resulting from hypomonoaminergic function[2].

[1]. Ipsen and IRLAB Enter Exclusive Worldwide Licensing Agreement Aimed to Improve the Lives of People Living with Parkinson’s Disease.
[2]. S Hjorth, et al. (3 S)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine (IRL752) -a Novel Cortical-Preferring Catecholamine Transmission- and Cognition-Promoting Agent. J Pharmacol Exp Ther. 2020 Sep;374(3):404-419.

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Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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