PNB-001 |
| Catalog No.GC71040 |
PNB-001 est un Ligand sélectif et antagoniste de la cck2 actif par voie orale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1528760-09-9
Sample solution is provided at 25 µL, 10mM.
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PNB-001 (100 nM, 30 min) blocks the CCK4- and CCK5-induced contractions in rat duodenum[1].
PNB-001 (5 and 20 mg /kg, p.o.) shows anti-inflammatory activity, and protects rats against Indomethacin induced ulceration[1].
References:
[1]. Lattmann E, et al. Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease. Medchemcomm. 2017 Feb 17;8(3):680-685.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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