Protein deglycase DJ-1 against-1 |
| Catalog No.GC62065 |
La protéine déglycase DJ-1 contre-1, un composé de liaison DJ-1, cible de manière dépendante DJ1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 724737-74-0
Sample solution is provided at 25 µL, 10mM.
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Protein deglycase DJ-1 against-1, a DJ-1-binding compound, dependently targets DJ1. Protein deglycase DJ-1 against-1 penetrates through the blood brain barrier (BBB). Protein deglycase DJ-1 against-1 is used as a neuroprotective agent and has the potential for Parkinson’s disease research[1].
Protein deglycase DJ-1 against-1 (compound-23; 1 mg/kg; IP; pretreatment one hour; daily; for 4 days) significantly restores MPTP induced locomotion, dopaminergic neuronal cell death and dopamine content in DJ-1(+/+) mice but not in DJ-1(-/-) mice[1].
[1]. Kazuko Takahashi-Niki, et al. DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson’s disease.
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