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(R)-TTBK1-IN-1

Catalog No.GC70719

(R)-TTBK1-IN-1 est un inhibiteur puissant, sélectif et perméable au cerveau de la Tau Tubuline kinase 1 ttbk1.

Products are for research use only. Not for human use. We do not sell to patients.

(R)-TTBK1-IN-1 Chemical Structure

Cas No.: 2735015-59-3

Taille Prix Stock Qté
1 mg
160,00 $US
En stock
5 mg
351,00 $US
En stock
10 mg
558,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
(R)-TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor. (R)-TTBK1-IN-1 is an enantiomer of TTBK1-IN-1 . (R)-TTBK1-IN-1 can be used in the research of alzheimer’s disease and related tauopathies. (R)-TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

References:
[1]. Halkina T, et, al. Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo. J Med Chem. 2021 May 13;64(9):6358-6380.

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